Joseph Goldstein

Joseph Goldstein


Joseph L. Goldstein is an American Biochemist born on 18 April 1940, In Kingstree, South Carolina.

Family Background:

He is the son of Isadore E. Goldstein and his wife Fannie. His father owned a clothing store. Joseph is the only son of his parents.

Personal Life:

He never married in his life. He likes listening to classical music in his leisure time.


He started his education at Lee University in Lexington and graduate with B.S degree in chemistry. Then he attended the Southwestern Medical school of the University of Texas Health science center in Dallas and received His MD degree in 1966.


After receiving his MD degree he moved to Boston as an Intern and resident in Medicine at the Massachusetts General Hospital. Here he met Michael Brown. Their deep friendship and long-term collaborate most useful in future. After completing his residency, He moved to the National Institutes of Health in Bethesda, Maryland. Here he worked in Biochemical genetics and returned to the Southwestern Medical Center in 1972 and accepting the post as the head of the newly-created Division of Medical Genetics. After he had been appointed as the assistant professor in Seldin’s Department of Internal Medicine. Around this time, He had collaborated with Michael Brown and they focused study on the cholesterol present in the human bloodstream. Their intensive research had led to the discovery that low-density lipoproteins in the primary cholesterol-carrying particles are withdrawn from the bloodstream into the body’s cells by receptors on the cells’ surface. They had also performed research work on genetic hypercholesterolemia. In 1977, Joseph had been made the chairman of the Department of Molecular Genetics at the Texas Health Science center at Dallas and also had been made Paul J. Thomas professor of medicine and Genetics. During the years of 1973 to 1985, Joseph and Michael together published over 100 major papers. In 2015, Joseph Goldstein had been elected as the life trustee of The Rockefeller University. In the recent years, Joseph authored a series of essays considering science as a creative pursuit. These essays, explore the links between the Art and Science which appear in the journal ‘Nature Medicine.’

Unknown Facts:

  • His full name is Joseph Leonard Goldstein.
  • He shared the Louisa Gross Horwitz Prize with Michael S. Brown.

Master Stroke:

  • Joseph along with his colleague Michael Brown made many key contributions to the understanding of cholesterol in the bloodstream of human beings.

Awards and Achievements:

  • In 1985, He and Michael Brown jointly received the Nobel prize.
  • In 1988, He received the National Medal of Science in the field of molecular genetics.

What can we learn from him??

Like Joseph Goldstein, never think about others opinions. do your research continuously in any field.

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